There are components installed in LL to make it run smoothly in VirtualBox. When you boot the system it'll run a check to see if it is being run from within VirtualBox and you are likely seeing the message that it's NOT running in VBox. In other words, if you were running Windows and installed LL into VirtualBox on Windows, the components I'm talking about would make LL run better in VirtualBox. Since that's not what you're doing, you're just seeing a message produced during initial boot check confirming that you're not running from within VirtualBox. Nothing is wrong, but the message does cause a lot of confusion.
I didn't read through whole thread referenced by firenice03, but I'm assuming there are instructions there to remove those components if seeing the message really bothers you.