What hardware have you, and how old is it ?
Have it always behaved like that (from brand new), and if not - where there any changes done before you noticed it first tome ?
It's an old P/C that's why I chose Linux Lite.
I had to use "noapic" to get LL to install
I tried Mint Peppermint UbuntuStudio all Distro's had the same trouble
I have onboard chip-set realtek alc883 It works fine and plays fine if I don't move the Mouse over an open window.
Example, playing song in Fire Fox, open Volume control, Moving the Mouse over the menu causes a scratching sound or popping sound.
Opening the terminal and Moving the Mouse over each line of text produces a sound similar to bare wire touching speaker post intermittently.
It's always done this. I hoped the update after installing would have fix it, but no